Author: Department of Surgery

After an extensive national search, Chandrajit P. Raut, MD, MS, has been named division chief of Surgical Oncology at Brigham Health, effective October 1, 2019.

Dr. Raut, who is also a professor of surgery at Harvard Medical School and surgery director of the Center for Sarcoma and Bone Oncology at Dana-Farber Cancer Institute, is a graduate of Stanford University (BA/BS), University of Oxford (MSc) and Harvard Medical School (MD). He completed a general surgery residency at Massachusetts General Hospital followed by a surgical oncology fellowship at MD Anderson Cancer Center. 

Dr. Raut is a committed clinician who specializes in the multidisciplinary care of patients with soft tissue sarcoma. He is also a prolific researcher, and currently has a multi-PI R01 grant to evaluate an innovative drug-eluting film to be placed in the surgical bed to reduce tumor local recurrence rates. Additionally, he is co-PI on a multi-institutional phase II clinical trial evaluating five years of adjuvant imatinib for primary GIST, co-investigator on an international phase III randomized clinical trial evaluating the use of preoperative radiation therapy for retroperitoneal sarcomas, and a member of The Cancer Genome Atlas Sarcoma (TCGA-SARC) working group of the National Institutes of Health (NIH)/National Cancer Institute (NCI). 

Dr. Raut serves as section editor for sarcoma in the journals Cancer and Annals of Surgical Oncology, associate editor for the journal Sarcoma and an editorial board member for the journal ACS Case Reports in Surgery. He has authored over 200 papers and over 30 book chapters and also serves as the program director of the Dana-Farber/Partners Cancer Care Surgical Oncology Fellowship. 

Dr. Mannick served as Moseley Professor of Surgery at Harvard Medical School between 1976-1994. He was a national and international leader in vascular surgery, surgical research and a dedicated educator who provided seminal contributions in transplantation immunology and in understanding the role of the intrinsic immune system in burns and other forms of acute injury.

Dr. Mannick contributed many successful techniques to the practice of vascular surgery. This includes vein grafts to reconstruct the tibial and peroneal arteries, the reduction of mortality from abdominal aortic aneurysm repair from more than five percent to less than two percent through the use of volume loading and minimal dissection of the aorta and iliac arteries. In addition, the use of axillo-femoral and femoro-femoral grafts to correct aortoiliac occlusive disease in certain high risk patients, and the demonstration that autogenous tissue reconstruction techniques can be applied with very high rates of long term success in over ninety percent of patients with limb-threatening femoropopliteal and infrapopliteal occlusive disease.

Also a skilled administrator, Dr. Mannick made a major contribution to the growth of the Department of Surgery at the Brigham and the services it could offer during the planning and formation of the new Brigham and Women’s Hospital which opened in 1980.

Click here to view Dr. Mannick’s obituary.

Please join us in welcoming Shailesh Agarwal, MD, as a new faculty member in the Department of Surgery.

Shailesh Agarwal, MD
Associate Surgeon, Division of Plastic and Reconstructive Surgery

Dr. Agarwal received his undergraduate degree from the University of Michigan and received his medical degree from the University of Chicago Pritzker School of Medicine. He then completed his residency training in Plastic Surgery and an NIH-funded post-doctoral research fellowship at the University of Michigan. He subsequently completed a fellowship in microsurgical reconstruction at the University of Chicago.

Dr. Agarwal’s clinical interests include reconstruction of the breast, lymphatic system, chest wall, trunk/lower extremity, and head/neck, as well as gender surgery. Dr. Agarwal’s laboratory research is centered on genetic and epigenetic re-programming to modify cell function for tissue regeneration.